The Different Effects of High Phosphate Levels in Chronic Kidney Disease
نویسندگان
چکیده
As renal function declines, the accumulation of phosphate adversely affects mineral homeostasis and bone turnover. The consequences of this imbalance include secondary hyperparathyroidism (2oHPT), osteodystrophy, and vascular calcification. High phosphate levels are a key factor in the pathogenesis of 2oHPT. Hyperphosphatemia is common in uraemic patients due to a reduced excretion of phosphate and because routine dialysis cannot remove the absorbed phosphate. Studies in uraemic rats have shown that phosphate loading accelerates development of 2°HPT, whereas dietary phosphate restriction can prevent and even arrest 2°HPT in animal models of renal The different effects of high phosphate levels in chronic kidney disease
منابع مشابه
Correlation between the Level of Creatinine, Serum Cardiac Troponines and Left Ventricle Function Tests in Patients with Chronic Renal Diseases without Acute Coronary Syndrome
Background and Objectives: The aim of this study was to survey the relationship between the level of creatinine,cardiac troponins serum and the function of the left ventricle in patients with kidney insufficiency,without acute coronary syndrome. Materialsand Methods:The sample was150 patients with nondialysis chronic kidney disease without acute coronary syndrome, hospitalized at I...
متن کاملThe Effect of Regular Aerobic Exercise with Garlic Extract on Heart Apoptosis Regulatory Factors in Chronic Kidney Disease
Objective: Physical activity and herbal medicine can inhabit apoptosis with two different mechanisms. The aim of this study was to assess the combined effect of regular aerobic exercise with garlic extract on heart apoptosis regulatory factors in aged rats with chronic kidney disease. Materials and Methods: In this experimental research, 42 aged male Wistar rats (48-52 weeks) were selected and...
متن کاملEvaluation of Hypothyroidism in Patients with Chronic Kidney Disease in Western Iran
Background and Objective: Chronic kidney disease (CKD) determined by permanent kidney damage. Due to the similarity of clinical symptoms of hypothyroidism with CKD, hypothyroidism may be neglected and remain untreated. The goal of our study was to evaluate the rate of hypothyroidism in CKD patients who need hemodialysis. Materials and Methods: This is a cross-sectional research. The sampling ...
متن کاملVitamin D deficiency in children with Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) and factors affecting response to cholecalciferol therapy: A quasi-experimental study from low-middle income setting
Background and Objective: Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) is characterized by hypocalcemia, hyperphosphatemia and abnormal vitamin D (VD) metabolism resulting in high parathyroid hormone secretion. The objective of the study was to determine VD status in children with CKD-MBD and the effect of cholecalciferol therapy in these children. Methods: This quasi-experimental st...
متن کاملProposed Method for Predicting COVID-19 Severity in Chronic Kidney Disease Patients Based on Ant Colony Algorithm and CHAID
Background and Objective: The COVID-19 pandemic is a phenomenon that has infected and killed many people worldwide. Underlying diseases such as diabetes mellitus, heart failure, and chronic kidney disease (CKD) can affect the severity of COVID-19 and aggravate patients' condition. This study aimed to predict the severity of the COVID-19 disease in CKD patients by combining feature selection and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2005